Message From Our Founder

It has been over 10 years since I founded Collaborations Pharmaceuticals, Inc. with the idea to build on my prior 20 years plus background and interests in developing software for drug discovery as well as research on rare and neglected diseases. Little did I know that in subsequent years the interest in machine learning and artificial intelligence (AI) would take off in the way that it has.

Today we are faced with the massive ‘frontier labs’ competing to attract large pharma companies and seemingly becoming pharmas themselves as they buy smaller biotech companies and develop their own labs to do R&D. These are organizations with little or no drug discovery expertise who assume that they know it all because they have ‘AI’. Their hubris is real. We, in contrast, are small, have not accepted any dilutive funding, and we have kept our feet firmly grounded. AI is just another tool to help us.

Over the years we have also had to pivot to performing fees for service work for small pharmas all the way to massive consumer product companies. We have also licensed our software to companies so they can use it themselves. These efforts have helped us to understand real challenges that companies face in order to make progress and get their products in the clinic or approved.

In addition to developing software and using this to help other companies, a third element of the company is developing our own treatment pipeline and intellectual property. This was initially focused on small molecule antivirals and quickly expanded to include an enzyme replacement therapy for an ultra-rare Batten Disease CLN1. In the former we have developed a small molecule and had a pre-IND meeting with the FDA for Ebola. In the latter case, we have brought a treatment through IND enabling toxicology and GMP manufacturing with funding from the NIH and our own investment.

We have clearly leveraged a range of external collaborations with other companies, institutes, and academic labs as well as our own labs to enable such progress. We simply could not do it alone. This experience has been incredibly valuable and demonstrates that while AI has a key role, much of the process of R&D is not something that it will solve alone; therefore, human experts are still an essential component.

My company’s over a decade of expertise in applying AI to drug and product discovery as well as our hands-on synthesis and testing all the way through to regulatory filing are unique capabilities. We have demonstrated already that we have a place in the ecosystem, and many multibillion-dollar companies are our partners and trust our expertise. If you would like to learn about how we can help your company design new molecules, evaluate their properties, or create new tools to overcome your bottlenecks, you can learn more at our website. In addition, we have demonstrated that a small company can make meaningful progress in developing treatments for rare and neglected diseases. If you would be interested in working with us to help, bring these to the waiting patients, please get in touch. No disease is too small®.

Cheers,
Sean Ekins, Ph.D., D.Sc., CEO